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Rockville-based Neuralstem, NFL team up on brain injury

Neuralstem Inc., of Rockville, which is developing products to treat central nervous system disorders with patented stem cell technology, said it is working with the National Football League Alumni Association to develop a trial for treating NFL alumni members suffering from traumatic brain injuries.

Neuralstem is proposing using NSI-189, a drug that it developed and which is being tested as a treatment for major depressive disorder.

NSI-189 appears to work by stimulating neurons in the hippocampus, a region of the brain that atrophies in depression and which Neuralstem believes could also be implicated in brain injury.

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