As president and CEO of Melwood, Cari DeSantis oversees 1,500 employees, including 900 employees with differing abilities. Melwood, which is based in Upper Marlboro, provides employment, job training, life skills improvement and partners with agencies like Fort Meade or NASA Goddard to provide opportunities to clients.
From 2010 to 2012, DeSantis also led a national workgroup to modernize government health and human services.
DeSantis also has volunteered on humanitarian missions in Central America and penned four books. She was a founder of Wilmington Women in Business.