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NIH zebrafish research included in USPS stamp collection 

NIH zebrafish research included in USPS stamp collection 

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The image was taken by NICHD's Daniel Castranova, an aquatic research specialist, with assistance from former trainee Bakary Samasa. The research was conducted in the Section on Vertebrate Organogenesis, led by principal investigator Brant Weinstein, Ph.D. (Photo courtesy of USPS)
The image was taken by NICHD’s Daniel Castranova, an aquatic research specialist, with assistance from former trainee Bakary Samasa. The research was conducted in the Section on Vertebrate Organogenesis, led by principal investigator Brant Weinstein, Ph.D. (Photo courtesy of USPS)

A microscopy image created by researchers at the Bethesda-based National Institutes of Health researchers is part of the “Life Magnified” stamp panel issued Monday by the United States Postal Service (USPS®). The NIH zebrafish image, which was taken to understand lymphatic vessel development in the brain, merges 350 individual images to reveal a juvenile zebrafish with a fluorescently tagged skeleton, scales and lymphatic system.

The image was taken by NICHD’s Daniel Castranova, an aquatic research specialist, with assistance from former trainee Bakary Samasa. The research was conducted in the Section on Vertebrate Organogenesis, led by principal investigator Brant Weinstein, Ph.D. The lab is devoted to understanding mechanisms guiding the formation of blood and lymphatic vessels. The image also received top honor in the 46th annual Nikon Small World Photomicrography Competition in 2020.

Findings from the microscopy image were published in Circulation Research and featured on the journal’s cover. The work led to a groundbreaking discovery that zebrafish have lymphatic vessels inside their skull. These vessels were previously thought to occur only in mammals, and their discovery in fish could expedite and revolutionize research related to treatments for diseases that occur in the human brain, including and Alzheimer’s disease.